In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%, while a 5% Argireline formula applied for 28 days did almost the same with a decrease in wrinkle depth by 16.26%. The manufacturer did several studies to prove that Argireline really works and it does (just not as well as Botox). We especially recommend it if you are after skin brightening as this seems to be the strongest point of MAP. We have better news about the other two things: in-vitro data shows that MAP can boost collagen synthesis similar to AA (though in the case of AA it's proven in-vivo) and even better, MAP is proven to work as a skin brightener in-vivo (on real people).īottom line: when it comes to vitamin C derivatives, MAP is definitely an option. Regarding the three magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener), there is no published data about MAP's antioxidant or photoprotection capabilities. Even if it does, we don't know how good the conversion rate is (but to be fair the same is true for all other derivatives). The good news is that in-vitro data shows that MAP does convert, but the bad news is we do not really know if the same is true on real, living human skin. Moreover, derivatives not only have to be absorbed into the skin, they also have to be converted into pure AA. What is not so good is that, as the great review study about vitamin C derivatives in the Journal of Cosmetic Dermatology writes, MAP is "at very best, poorly absorbed in comparison to AA." MAP does solve the stability problem: it's stable up to pH 7, so far so good. Even though some of its effects are more hyped up than backed up, it is still a nice to have on many ingredient lists. Overall, we think that caffeine is a very versatile and biologically active ingredient. A 2017 study compared a 0.2% caffeine liquid with a 5% Minoxidil (an FDA approved active to treat baldness) solution and found that " a caffeine-based topical liquid should be considered as not inferior to minoxidil 5% solution in men with androgenetic alopecia", or English translation means that the caffeine liquid was pretty much as good as the FDA-approved Minoxidil stuff. We have found some recent and promising research to back this up. The theory is that it can inhibit the activity of the 5-α-reductase enzyme that plays an important role in hair loss and allows a renewed growth phase of the hair. Last, but not least, we have to write about caffeine and hair growth. But here again, the evidence that it actually makes a measurable, let alone visible, improvement on actual human beings is limited (we could find only some animal skin studies or caffeine being combined with other actives). In theory, it can speed up the lipolysis process (the "fat burning" by our cells) and stimulate the draining lymph system that might lead to the improvement of cellulite. Though conventional wisdom and anecdotal evidence says that this property is helpful for dark under-eye circles and puffy eyes, we have to mention that the double-blind research we have found about a 3% caffeine gel concluded that " the overall efficacy of the selected caffeine gel in reducing puffy eyes was not significantly different from that of its gel base." But you know, the proof is in the pudding.Īnother thing Caffeine is used for in body care products is its anti-cellulite effects. Iron Oxides (Ci 77491),Iron Oxides (Ci 77492),Iron Oxides (Ci 77499)Ī well-known thing about Caffeine is that it improves the microcirculation of the blood vessels. Vinyl Dimethicone/Methicone Silsesquioxane CrosspolymerĪmmonium Acryloyldimethyltaurate/VP Copolymer Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer ,Īmmonium Acryloyldimethyltaurate/VP Copolymer , Water\Aqua\Eau, Methyl Trimethicone, Trimethylsiloxysilicate, Dimethicone, Butylene Glycol, Phenyl Trimethicone, Neopentyl Glycol Diheptanoate, Niacinamide, Hydroxyethyl Urea, Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone, Glycerin, Sodium Polyaspartate, Ascorbyl Glucoside, Caffeine, Phytosphingosine, Magnesium Ascorbyl Phosphate, Resveratrol, Sodium Hyaluronate, Polygonum Cuspidatum Root Extract, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Salicylic Acid, Sigesbeckia Orientalis (St.Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone , Formula is formulated with the goodness of vitamin C, hyaluronic acid helps hydrate and plump fine, dry lines, and caffeine helps energize.
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